Majocchi´s granuloma – case report.

Abstract

Dermatophytic granuloma, also known as Majocchi's Granuloma (GM) is characterized by granulomatous, peripollicular inflammation. It was described by Domenico Majocchi (1883). GM is a rare entity produced by dermatophytes that causes a deep infection of the dermis and subcutaneous cellular tissue, although in the initial description was related to dermatophyte Trichophyton tonsurans, other non-dermatophyte etiological agents (Phoma, Aspergillus, Malbranchea) were subsequently reported. GM appears in both healthy and immunocompromised individuals and is characterized by nodules, plaques, and papules that affect areas exposed to trauma. Generally, it affects upper and lower extremities (forearms, hands, legs, and knees or ankles), and occasionally, it appears on the scalp and face. The clinical, mycologic, and/or cytologic diagnosis should be confirmed by the demonstration of perifollicular granulomatous inflammation by histologic examination.There is no response to topical antifungal therapy and therefore requires systemic therapy. The following describes a clinical case in a 6-year-old boy with facial involvement, who presented a plaque-like lesion that affected the nose, with a month of evolution.  A diagnostic biopsy was performed that detected deep fungal infection; being treated with terbinafine with complete response.

Keywords: Majocchi’s granuloma; tinea; terbinafine