Effectiveness of platelet rich-fibrin in third molars extractions. Systematic review

Abstract

Fibrin-rich plasma (PRF) is an autologous material obtained from blood centrifugation, considered as an adjuvant in the cellular regeneration of soft tissues and bone, as it contains a high concentration of platelets, fibrin, leukocytes and growth factors that have a significant potential in tissue repair. The objective is to elaborate a systematic review of the effectiveness of fibrin-rich plasma in third molar extractions, using the PRISMA critical analysis guidelines, in Scielo, PubMed and ScienceDirect web portals by manual search. Regarding the studies reviewed, 25% concluded that no significant differences were found when using PRF, while 75% of the publications reported that the application of PRF improved and/or accelerated the tissue healing process, reduced the pain during the recovery process and decreased the incidence of infections. From the results found, it is concluded that the application of fibrin-rich plasma brings potential advantages in the post-surgical of third molar surgeries.

Key words: Dentistry, Oral surgery, Platelet rich fibrin, Systematic review, Third molar.